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J Kopecek Selected Research

meso-chlorin e(6) monoethylene diamine

3/2008Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs.
7/2001Combination chemotherapy and photodynamic therapy of targetable N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin/mesochlorin e(6)-OV-TL 16 antibody immunoconjugates.
11/2000Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance.
3/2000Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-Mesochlorine e6 and adriamycin conjugates in combination treatments.

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J Kopecek Research Topics

Disease

16Carcinoma (Carcinomatosis)
12/2007 - 01/2000
7Neoplasms (Cancer)
07/2001 - 03/2000
2Ovarian Neoplasms (Ovarian Cancer)
12/2007 - 07/2001
2Barrett Esophagus (Barrett's Esophagus)
07/2001 - 09/2000
2Necrosis
10/2000 - 04/2000
1Renal Cell Carcinoma (Grawitz Tumor)
03/2008
1Osteoporosis
06/2004
1Rheumatoid Arthritis
06/2004
1Colonic Neoplasms (Colon Cancer)
01/2004
1Ulcerative Colitis
07/2001
1Hepatocellular Carcinoma (Hepatoma)
01/2001
1Inflammation (Inflammations)
09/2000
1Colitis
09/2000
1Lymphoma (Lymphomas)
05/2000
1Burkitt Lymphoma (Burkitt's Lymphoma)
05/2000

Drug/Important Bio-Agent (IBA)

19hydroxypropyl methacrylateIBA
03/2008 - 01/2000
11Doxorubicin (Adriamycin)FDA LinkGeneric
03/2008 - 01/2000
10N-(2-hydroxypropyl)methacrylamideIBA
03/2008 - 01/2000
5Pharmaceutical PreparationsIBA
07/2001 - 05/2000
4meso-chlorin e(6) monoethylene diamineIBA
03/2008 - 03/2000
4PolymersIBA
06/2004 - 01/2000
2AntigensIBA
07/2001 - 07/2001
2Monoclonal AntibodiesIBA
07/2001 - 07/2001
2Fluorescein-5-isothiocyanate (FITC)IBA
10/2000 - 05/2000
1ThiophenesIBA
03/2008
1Cathepsin KIBA
06/2004
1Cysteine Proteases (Cysteine Protease)IBA
06/2004
1Galectin 3 (LGALS3)IBA
01/2004
1LigandsIBA
01/2004
1CarbohydratesIBA
01/2004
1Proteins (Proteins, Gene)FDA Link
01/2004
1RNA (Ribonucleic Acid)IBA
01/2004
1SugarsIBA
01/2004
1geldanamycinIBA
08/2001
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2001
1Immunoglobulin Fab FragmentsIBA
07/2001
1Biological ProductsIBA
07/2001
1Wheat Germ AgglutininsIBA
07/2001
1Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2001
1AgglutininsIBA
07/2001
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
07/2001
1Peanut AgglutininIBA
07/2001
1Phosphatidylinositols (Phosphatidylinositol)IBA
07/2001
1CaspasesIBA
04/2001
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
11/2000
1Annexin A5IBA
10/2000
1Propidium (Propidium Iodide)IBA
10/2000
1Thomsen-Friedenreich antigenIBA
09/2000
1LectinsIBA
09/2000
1Peptides (Polypeptides)IBA
05/2000
1EpitopesIBA
05/2000
1Texas redIBA
05/2000
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2000
1Caspase 9IBA
04/2000
11-phenyl-3,3-dimethyltriazene (PDT)IBA
03/2000

Therapy/Procedure

3Therapeutics
07/2001 - 03/2000
3Photochemotherapy (Photodynamic Therapy)
07/2001 - 03/2000
2Drug Therapy (Chemotherapy)
07/2001 - 03/2000
2Combination Drug Therapy (Combination Chemotherapy)
07/2001 - 03/2000
1Dye Lasers
07/2001